2013 of 2013
Randomization is closed!
effective February 19, 2018
150 patients to go
Content: 1) Current status of co-authorships per site and patients required for another collaborative authorship; 2) Still 200 patients to go!
250 patients to go!
Content: 1) PROBESE is ready for the final round; 2) Study protocol published in TRIALS; 3) PROBESE Steering Committee meeting during Euroanesthesia in GENEVA
Content: How to deal with: 1) Early discharge from hospital (before postop day 5); 2) Patients lost to follow up; 3) Randomization not followed by adequate study treatment
Content: 1) Oxygen Stress test - extension of study protocol for additional preop measurement of SpO2 in supine; 2) Introduction of further sub-studies
Content: 1) PROBESE continues - News from the Steering Committee meeting in London; 2) Publication of the study protocol in TRIALS
Content: 1) Complete your data for first interim analysis; 2) Adherence to mechnical ventilation protocol
Content: PROBESE is extended!
Content: Please complete online data entry
Content: 1) Online Monitoring started; 2) Ventilatory settings during recruitment maneuver;
Content: 1) Need for Screening log file; 2) Follow up on day 90; 3) How to calculate consumption of volatiles during anesthesia; 4) Auto-PEEP
Content: 1) Monitoring and completeness of data; 2) Early discharge and follow up; 3) Steps for centers that obtained final IRB approval;
Content: 1) PROBESE is official study of the ESA Clinical Trial Network (CTN); 2) Reporting of Adverse Events; 3) Follow up after protocol violation; 4) Deviation from the mechanical ventilation protocol
Content: 1) Summary of National Coordinators and attending Local Investigators; 2) Funding and Insurance issues; 3) New study protocol version 2.4.2; 4) Applications for sub-studies